Quality Factory Sells Top Purity 99% 5-CHLORO-2-NITROANISOLE 6627-53-8 with Safe Delivery
- Molecular Formula: C7H6ClNO3
- Molecular Weight: 187.583
- Appearance/Colour: slightly yellow to green crystalline powder
- Vapor Pressure: 0.00389mmHg at 25°C
- Melting Point: 70-72°C(lit.)
- Refractive Index: 1.559
- Boiling Point: 289.1 ºC at 760 mmHg
- Flash Point: 128.7 ºC
- PSA: 55.05000
- Density: 1.366 g/cm3
- LogP: 2.78000
5-CHLORO-2-NITROANISOLE(Cas 6627-53-8) Usage
InChI:InChI=1/C7H6ClNO3/c1-12-7-4-5(8)2-3-6(7)9(10)11/h2-4H,1H3
6627-53-8 Relevant articles
COMBINATION THERAPIES FOR TREATMENT OF CANCER
-
Paragraph 323, (2016/04/09)
Combination therapies for treatment of c...
COVALENT INHIBITORS OF KRAS G12C
-
Paragraph 0461, (2014/09/30)
Irreversible inhibitors of G12C mutant K...
Reactions of Organic Anions, 147.- Simple and General Synthesis of Hydroxy- and Methoxyindoles via Vicarious Nucleophilic Substitution of Hydrogen
Makosza, Mieczyslaw,Danikiewicz, Witold,Wojciechowski, Krzysztof
, p. 203 - 208 (2007/10/02)
A simple synthesis of 4-, 5-, 6-, and 7-...
Methoxylation of 3,4-dinitrochloro(bromo)benzene
Varenikova, S. F.,Nekhoroshev, A. A.,Sevbo, D. P.
, p. 1651 - 1652 (2007/10/02)
-
6627-53-8 Process route
-
-
124-41-4
sodium methylate
-
-
610-40-2
3,4-dinitro-chlorobenzene
-
-
89-21-4
4-chloro-2-nitroanisole
-
-
6627-53-8
1-chloro-3-methoxy-4-nitrobenzene
| Conditions | Yield |
|---|---|
|
In
methanol;
for 0.5h;
|
55%
|
|
In
methanol;
for 0.5h;
Product distribution;
|
82 % Chromat.
18 % Chromat. |
-
-
611-07-4
5-chloro-2-nitrophenol
-
-
74-88-4
methyl iodide
-
-
6627-53-8
1-chloro-3-methoxy-4-nitrobenzene
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 16h;
|
30 g
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 16h;
|
30 g
|
6627-53-8 Upstream products
-
123-91-1
1,4-dioxane
-
67-56-1
methanol
-
672295-04-4
(5-chloro-2-nitro-phenyl)-phenyl sulfone
-
124-41-4
sodium methylate
6627-53-8 Downstream products
-
860734-15-2
2-methoxy-4-(methylsulfanyl)-1-nitrobenzene
-
27848-31-3
bis-(3-methoxy-4-nitro-phenyl)-sulfide
-
875241-67-1
2-methoxy-1-nitro-4-phenoxy-benzene
-
704-14-3
3-methoxy-6-nitro-phenol