Product
Chemical plants supply high-quality 2-CHLORO-3-METHYLBENZO(B)THIOPHENE 3216-47-5 in bulk
- Molecular Formula: C9H7 Cl S
- Molecular Weight: 182.674
- Vapor Pressure: 0.00208mmHg at 25°C
- Melting Point: 40 °C
- Boiling Point: 299.8°Cat760mmHg
- Flash Point: 178.7°C
- PSA： 28.24000
- Density: 1.298g/cm3
- LogP: 3.64010
2-CHLORO-3-METHYLBENZO(B)THIOPHENE(Cas 3216-47-5) Usage
|
General Description |
2-Chloro-3-methylbenzo(b)thiophene is a chemical compound with the molecular formula C9H7ClS. It is a chlorinated derivative of benzo(b)thiophene, which is a heterocyclic organic compound. This chemical is used in the synthesis of various pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. It is also used as an intermediate in the manufacturing of other organic compounds. 2-Chloro-3-methylbenzo(b)thiophene is a yellowish crystalline solid with a melting point of around 37-39°C and is moderately soluble in organic solvents. It is important to handle this compound with care as it can be harmful if ingested, inhaled, or in contact with the skin. |
InChI:InChI=1/C9H7ClS/c10-5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6H,5H2
3216-47-5 Relevant articles
-
van Zyl et al.
, p. 2916 (1961)
-
-
Neidlein,Mrugowski
, p. 513,516 (1975)
-
Synthesis of [1]Benzothieno[2,3- b ]quinolines via Transition-Metal-Free [3+3] Annulation of Nitroarenes and Benzo[ b ]thiophen-3-ylacetonitrile or 3-(Phenylsulfonylmethyl)benzo[ b ]thiophene Carbanions
Nowacki, Micha?,Wojciechowski, Krzysztof
, p. 3794 - 3800 (2017)
Benzo[ b ]thiophen-3-ylacetonitriles or ...
Thiophenol-mediated hydrogen atom abstraction: An efficient tin-free procedure for the preparation of cyclopentane derivatives
Beaufils, Florent,Denes, Fabrice,Renaud, Philippe
, p. 2563 - 2566 (2004)
(Matrix Presented) An efficient procedur...
Method for synthesizing 3 - halo methyl benzofuran compounds
-
Paragraph 0028; 0029; 0047; 0048; 0049, (2019/03/21)
The invention provides a method for effi...
IDO inhibitors
-
Page/Page column 313, (2018/09/02)
Presently provided are methods for (a) m...
D1-like receptors distinguishing thieno-azecine regioisomers
Abdel-Fattah, Mohamed A. O.,Abadi, Ashraf H.,Lehmann, Jochen,Schweikert, Peter M.,Enzensperger, Christoph
, p. 1679 - 1686 (2015/09/21)
Designing ligands with D1/D5 subtype sel...
3216-47-5 Process route
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
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![Benzo[b]thiophene](/upload/2026/4/63ee2ce7277641ff9ef38a4dff6fa8c4_d99ce2cf-c324-4e64-ad5a-103ffafbb171.png)
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95-15-8,11095-43-5
Benzo[b]thiophene
-
-
3216-47-5
3-chloromethylbenzothiophene
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
|
92%
|
|
With
hydrogenchloride;
In
water;
at 65 ℃;
for 1.5h;
|
90.7%
|
|
With
hydrogenchloride;
at 65 ℃;
|
74.5%
|
|
With
hydrogenchloride;
at 65 ℃;
|
74.3%
|
|
With
hydrogenchloride;
In
water;
at 65 ℃;
for 1.5h;
|
67%
|
|
With
hydrogenchloride;
In
water;
at 0 ℃;
for 0.333333h;
|
52%
|
|
With
hydrogenchloride;
at 65 ℃;
|
28%
|
|
With
hydrogenchloride;
at 60 ℃;
for 1h;
|
8%
|
|
With
hydrogenchloride;
|
|
|
With
hydrogenchloride; acetic acid;
|
|
|
With
hydrogenchloride;
In
benzene;
for 1.5h;
Ambient temperature;
|
|
|
With
hydrogenchloride;
at 60 ℃;
for 6h;
|
|
|
With
hydrogenchloride;
|
-
-
58432-15-8
3-(2-aminophenylthio)prop-1-yne
-
-
3216-47-5
3-chloromethylbenzothiophene
| Conditions | Yield |
|---|---|
|
3-(2-aminophenylthio)prop-1-yne;
With
hydrogenchloride;
In
water; acetone;
at 0 ℃;
for 0.0833333h;
Inert atmosphere;
With
tert.-butylnitrite;
In
water; acetone;
at 0 ℃;
for 0.25h;
With
sodium iodide;
In
water; acetone;
at 0 - 60 ℃;
for 9h;
|
45%
|
3216-47-5 Upstream products
-
50-00-0
formaldehyd
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95-15-8
Benzo[b]thiophene
-
107-30-2
chloromethyl methyl ether
-
7647-01-0
hydrogenchloride
3216-47-5 Downstream products
-
3216-48-6
2-(benzo[b]thiophen-3-yl)acetonitrile
-
7388-06-9
2-[ethyl-(benzo[b ]thiophen-3-ylmethyl)-amino]-ethanol; hydrochloride
-
850855-58-2
3-benzo[b ]thiophen-3-yl-2,2-dimethyl-1-phenyl-propan-1-one
-
1455-18-1
3-methylbenzothiophene
